Ecotoxicity potentials of residual paracetamol and personal care products (PCPs) in household waste in the University of Port Harcourt, Port Harcourt, Nigeria

Authors

  • P.E Kika Department of Animal and Environmental Biology, University of Port Harcourt, Port Harcourt, Nigeria Author
  • B.B Babatunde Department of Animal and Environmental Biology, University of Port Harcourt, Port Harcourt, Nigeria Author
  • K.C Ugoeze Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmaceutical Sciences University of Port Harcourt, Port Harcourt, Nigeria Author
  • N. Sikoki, F. D Nwanchukwu Department of Animal and Environmental Biology, University of Port Harcourt, Port Harcourt, Nigeria. Author
  • O.K Udeala Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmaceutical Sciences University of Port Harcourt, Port Harcourt, Nigeria Author

Keywords:

Household waste, Pharmaceuticals and personal care products (PPCPs), residual paracetamol

Abstract

This study evaluated the relative amount of Pharmaceutical and Personal Care Products (PPCPs) and paracetamol residues contained in household waste at the University of Port Harcourt, Port Harcourt, Nigeria. Residual paracetamol was analysed using a 6405 UV/Vis Spectrophotometer at the maximum wavelength (245nm) in 0.1N HCL. Student hostels had a mean paracetamol concentration of 0.67 mg/kg while the staff quarters recorded a mean concentration of 0.66 mg/kg. Solid waste analysis recorded 0.9 kg/capita/day and 1.1 kg/capita/day for the student hostel and staff quarters respectively. The student’s hostel recorded a mean percentage PPCPs value of 52.9% which was higher than that obtained in the staff quarters (45.9%) indicating that students disposed of more drugs in their waste than does the staff. The study showed that considerable amounts of PPCPs are disposed of in household waste at the study location and household waste is thus a viable pathway of PPCPs into the environment. Such practices could lead to the occurrence of the active ingredients of PPCPs in the environment with the potential to contaminate surface and ground water posing serious risk to human and ecologic health. It was recommended that appropriate return channels be established specially as a route for disposing of unused or expired drugs. Such routes should encourage stewardship of drugs by manufacturers from cradle to grave in an integrated green pharmacy approach.

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Published

2024-03-01

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How to Cite

Kika, P., Babatunde, B., Ugoeze, K., Nwanchukwu, N. S. F. D., & Udeala, O. (2024). Ecotoxicity potentials of residual paracetamol and personal care products (PCPs) in household waste in the University of Port Harcourt, Port Harcourt, Nigeria. Toxicology Digest, 1(1), 46-62. https://toxicologydigest.org.ng/index.php/home/article/view/31

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